The human body accepted the pig's kidney
Kidney transplantation treatment has reached a milestone desired for many centuries.
Lack of a transplantable kidney may prevent human deaths this time around. Impaired kidney function no longer needs to be continued through dialysis. Kidneys of other animals can be successfully replaced by adapting to human body. Kidneys brought from other animals will work in the human body just like human kidneys. The human body will be able to accept the kidneys of other animals without any hindrance, without any objection.
Surgeons at the University of Alabama in Birmingham have shown that this groundbreaking treatment is not just a matter of imagination, but may be possible in reality. The genetically modified pig's two kidneys were perfectly replaced, and the human body's normal immune system did not prevent the other animal from accepting the two kidneys. Accepted without objection.The fancy kidney transplant research paper was published in the January 19 issue of the American Journal of Transplantation, an international medical research journal. Researchers also say that the US Food and Drug Administration (FDA) has approved the use of this method in clinical trials.
In this situation, the only desirable thing for the doctors is the kidney of another animal. The process of transplanting the kidneys of other animals into the human body is called 'genotransplantation' in medical terms.
But there were some drawbacks to this approach. So in the sixties of the last century, attempts to transplant chimpanzee kidneys into humans have not been successful. Despite the fact that chimpanzees are very close to humans. Of the 13 kidney patients who received chimpanzee kidney transplants at that time, only 10 died within two to three weeks. Because the chimpanzee's kidneys did not want to accept the normal immune system of the human body. So the kidneys could not work in the human body for a long time. In eight decades of research, scientists and physicians have come up with the idea that the kidneys of pigs may be accepted by the human body. Because, in size, shape, the kidney of a pig is much like a human kidney. In the eighties, a patient's kidney was transplanted into a pig's body. But it did not remain active for more than 54 hours.
The reason for this was the resistance of the human body. Against organs taken from other animals. One of them is blood clotting. In the eighties, a patient who took a pig's kidney had a blood clot in a few days. Human blood pressure is also higher than that of pigs or non-human animals. It was not possible to take that extra pressure on the transplanted kidney taken from the pig.
So this time the researchers edited 10 genes of the pig's kidney in a different way in the laboratory. So that they function exactly like the human kidneys after transplantation into the human body. That kidney should not be considered as an external enemy of the normal immune system of the human body. As if that kidney does not cause the clotting of human blood. Blood circulation should continue in the human body. The work of improving those genes in pigs was done in a virus-free, fungus-free environment of all kinds. That pig was kept in the same environment for a long time.